Phospho-Estrogen Receptor alpha (Tyr537) Antibody

Gene:

ESR1

GendID:

2099

Weight:

66kDa

Format:

Liquid

Swiss-Prot:

P03372

Concentration:

1mg/ml

Shipping:

Ice bag

French translation:

anticorps

Clonality:

Polyclonal

Fragment:

Fab fragment

GeneAlias:

ESR1 ESR NR3A1

Epitope:

Phospho Tyr537

Reactivity:

Human,Mouse,Rat

Type:

primary antibody

Application:

WB,IHC,IF/ICC,ELISA

Unigene:

Hs.208124;Hs.744830;

Antigen:

Phospho-Estrogen Receptor alpha (Tyr537)

Application_advice:

WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Immunogen:

A synthesized peptide derived from human Estrogen Receptor- alpha around the phosphorylation site of Tyrosine 537.

Properties:

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Specificity:

Phospho-Estrogen Receptor- alpha (Tyr537) Antibody detects endogenous levels of Estrogen Receptor- alpha only when phosphorylated at Tyrosine 537.

Purification:

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Storage_Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Description:

The Phospho-Estrogen Receptor alpha (Tyr537) Antibody is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.