GeneAlias:ESR1 ESR NR3A1
Application_advice:WB 1:1000-3000, IF/ICC 1:100-1:500
Antigen:Phospho-Estrogen Receptor alpha (Thr311)
Immunogen:A synthesized peptide derived from human Estrogen Receptor-α (Phospho-Thr311).
Specificity:Estrogen Receptor-α (Phospho-Thr311) Antibody detects endogenous levels of Estrogen Receptor-α only when phosphorylated at EstrThr311.
Properties:If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Purification:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage_Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Description:The Phospho-Estrogen Receptor alpha (Thr311) Antibody is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.