Phospho-Leptin Receptor (Tyr986) Antibody

Gene:

LEPR

GendID:

3953

Reactivity:

Human

Weight:

96kDa

Swiss-Prot:

P48357

Format:

Liquid

Concentration:

1mg/ml

Shipping:

Ice bag

Application:

WB,ELISA

French translation:

anticorps

Clonality:

Polyclonal

GeneAlias:

LEPR DB OBR

Fragment:

Fab fragment

Epitope:

Phospho Tyr986

Application_advice:

WB 1:1000-3000

Type:

primary antibody

Unigene:

Hs.23581;Hs.723178;

Antigen:

Phospho-Leptin Receptor (Tyr986)

Immunogen:

A synthesized peptide derived from human Leptin Receptor (Phospho-Tyr986).

Specificity:

Leptin Receptor (Phospho-Tyr986) Antibody detects endogenous levels of Leptin Receptor only when phosphorylated at Tyr986.

Properties:

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Purification:

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Storage_Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Additional gene:

Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.

Description:

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.