TNF Receptor II Antibody

GendID:

7133

Weight:

48 KD

Swiss-Prot:

P20333

Format:

Liquid

Concentration:

1mg/ml

Shipping:

Ice bag

Gene:

TNFRSF1B

French translation:

anticorps

Clonality:

Polyclonal

Unigene:

Hs.256278;

Fragment:

Fab fragment

Antigen:

TNF Receptor II

Reactivity:

Human,Mouse,Rat

Application:

WB,IF/ICC,ELISA

Type:

primary antibody

GeneAlias:

TNFRSF1B TNFBR TNFR2

Immunogen:

A synthesized peptide.

Application_advice:

WB 1:500~1:1000 IF/ICC 1:100-1:500

Specificity:

TNF Receptor II Antibody detects endogenous levels of total TNF Receptor II.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Properties:

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage_Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Additional gene:

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

Description:

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.