Phospho-Caspase 8 (Tyr448) Antibody

GendID:

841

Reactivity:

Human

Weight:

57kDa

Gene:

CASP8

Swiss-Prot:

Q14790

Format:

Liquid

Concentration:

1mg/ml

Shipping:

Ice bag

French translation:

anticorps

Clonality:

Polyclonal

GeneAlias:

CASP8 MCH5

Unigene:

Hs.599762;

Fragment:

Fab fragment

Epitope:

Phospho Tyr448

Type:

primary antibody

Application:

WB,IHC,IF/ICC,ELISA

Antigen:

Phospho-Caspase 8 (Tyr448)

Application_advice:

WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Immunogen:

A synthesized peptide derived from human Caspase 8 (Phospho-Tyr448).

Specificity:

Caspase 8 (Phospho-Tyr448) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Tyr448.

Properties:

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Purification:

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Storage_Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Description:

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.