Mouse Low affinity immunoglobulin gamma Fc region receptor III (Fcgr3)

Tissue:

region

Latin name:

Mus musculus

Notes:

For research use only.

Additional_information:

MW: 37.2 kDa; Buffer composition: Tris-based buffer with 50% glycerol.

Description:

Recombinant Mouse Low affinity immunoglobulin gamma Fc region receptor III(Fcgr3),partial expressed in E.coli

Specifications:

Uniprot ID: P08508; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 31-215aa; Sequence information: Extracellular Domain; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.

Storage_and_shipping:

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.

Test:

A high affinity purification column was use to purify Mouse immunoglobulin gamma Fc region receptor III (Fcgr3) by Cusabio by chromatographic size exclusion.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Additional description:

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.