100ug
GEN602155
641 EUR
Concentration:
N/A
Immunoglobulin isotype:
IgG1
Tissue:
nerve
Clone:
3H411
Purification method:
Purified
Category:
Antibodies
Clonality:
Monoclonal
Source organism:
Human (Homo sapiens)
Host organism:
Mouse (Mus musculus)
Subcategory:
Mnoclonal antibodies
Also known as:
Nerve Growth Factor Receptor, p75, Low Affinity
Other gene names:
NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16
Gene name synonims:
NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16
Gene name:
NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16
Form/Appearance:
Supplied as a lyophilized powder. No preservatives added. Reconstitute with 100ul sterile ddH2O.
Tested applications::
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Radioimmunoassay (RIA)
Test:
A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75, (NGFR p75) by MBS Monoclonals by chromatographic size exclusion.
Species reactivity:
Canine, Feline, Human (Homo sapiens), Porcine, Rabbit (Oryctolagus cuniculus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names:
nerve growth factor receptor; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; p75 ICD; NGF receptor; OTTHUMP00000220318; OTTHUMP00000220319; TNFR superfamily, member 16; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD
Specificity and cross-reactivity:
Recognizes the human low affinity nerve growth factor receptor (NGFR p75). The epitope recognized maps within the third or fourth cysteine-rich repeats of the NGFR molecule (within aa1-160, extracellular domain of human p75). Species Crossreactivity: primate, canine, feline, porcine, rabbit, raccoon and sheep. Does not react with rat, mouse or chicken.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping:
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description:
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.