Nerve Growth Factor Receptor, p75NTR (Low-affinity NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR)

Concentration:

N/A

Tissue:

nerve

Immunoglobulin isotype:

IgG2A

Clone:

9G398

Category:

Antibodies

Clonality:

Monoclonal

Subcategory:

Mnoclonal antibodies

Host organism:

Mouse (Mus musculus)

Source organism:

Rat (Rattus norvegicus)

Also known as:

Nerve Growth Factor Receptor, p75NTR

Purification method:

Affinity Purified by affinity chromatography.

Form/Appearance:

Supplied as a liquid in PBS, pH 7.2. No preservative added.

Other gene names:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Gene name synonims:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Gene name:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Tested applications::

ELISA (EL/EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)

Other names:

nerve growth factor receptor; N/A; nerve growth factor receptor; NRH; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor

Species reactivity:

Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Test:

A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75NTR ( - NGF receptor, Gp80-LNGFR, p75 ICD, neurotrophin receptor p75NTR) by MBS Monoclonals by chromatographic size exclusion.

Storage and shipping:

Store the antibody at +4 degrees Celsius. For long-term storage, aliquot and keep at +4 degrees Celsius for up to one year. Do not freeze. Aliquots are stable for up to 4 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Note: We do not recommended adding glycerol as a cryopreservative.

Specificity and cross-reactivity:

Recognizes the extracellular domain of the neurotrophin receptor p75NTR in rat. MC192 antibody may be used for immunocytochemical localisation of rat cells expressing p75NTR, ELISA and western blot. Does not react with mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Description:

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.