Nerve Growth Factor Receptor, p75NTR (Low-affinity, NGF receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD)

Concentration:

N/A

Immunoglobulin isotype:

IgG

Tissue:

nerve

Clone:

9G396

Category:

Antibodies

Clonality:

Monoclonal

Subcategory:

Mnoclonal antibodies

Host organism:

Mouse (Mus musculus)

Source organism:

Rat (Rattus norvegicus)

Also known as:

Nerve Growth Factor Receptor, p75NTR

Purification method:

Affinity Purified by Protein G affinity chromatography.

Form/Appearance:

Supplied as a lyophilized powder, 1% BSA. Reconstitute with 100ul sterile ddH2O.

Other gene names:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Gene name synonims:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Gene name:

ngfr; N/A; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR; N/A

Tested applications::

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Other names:

nerve growth factor receptor; N/A; nerve growth factor receptor; NRH; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor

Species reactivity:

Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Test:

A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75NTR ( - NGF receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD) by MBS Monoclonals by chromatographic size exclusion.

Specificity and cross-reactivity:

Recognizes the extracellular domain of the neurotrophin receptor in p75NTR-expressing cells in rat spinal cord and brain. Does not cross react with p75NTR-expressing cells in other species.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Storage and shipping:

Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

Description:

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.