100ug
GEN649595
514 EUR
Other gene names:
N/A
Additional isotype:
IgG
Other names:
N/A
Gene name:
N/A
Concentration:
N/A
Gene name synonims:
N/A
Clone:
11K4
Tissue:
region
Immunoglobulin isotype:
IgG2b,k
Also known as:
CD16,32
Clonality:
Monoclonal
Category:
Antibodies
Host organism:
Mouse (Mus musculus)
Subcategory:
Mnoclonal antibodies
Source organism:
Rat (Rattus norvegicus)
Purification method:
Affinity Purified by Protein G affinity chromatography.
Tested applications::
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Form/Appearance:
Supplied as a liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.5mg/ml gentamicin sulfate.
Species reactivity:
Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Test:
A high affinity purification column was use to purify CD16,32 (CD16, CD32, Fc-gamma RII, FcRII, Fcgr2, Fcgr2b, Fc-gamma RIII, FcRIII, Fcgr3, IgG Fc Receptor II beta, IgG Fc Receptor III, Immunoglobulin gamma Fc Region Receptor II, Immunoglobulin gamma Fc Region Receptor III) by MBS Monoclonals by chromatographic size exclusion.
Storage and shipping:
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
About:
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
Specificity and cross-reactivity:
Recognizes rat FcR. Binds specifically to the Fc Receptor gamma III and II for all mouse strains tested. This antibody blocks Fc mediated binding of immunoglobulin to these molecules, and is useful as a means to block non specific binding in assays containing FcR expressing cell types.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description:
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.