IL3RA Antibody

Analyses:

WB

Target antigen:

IL3RA

Gene Name:

IL3RA

Raised in:

rabbit

Uniprot ID:

P26951

French translation:

anticorps

Product form:

freeze-dried

Clone:

Polyclonal antibody

Clonality:

Polyclonal antibody

Type of the antibody:

IgG polyclonal antibody

Purification:

Immunogen affinity purified.

Reacts with species::

human Predicted to work with: mouse, rat

Gene Full Name:

interleukin 3 receptor, alpha(low affinity)

Product configuration:

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Protein Name:

Interleukin-3 receptor subunit alpha(IL-3 receptor subunit alpha/IL-3R subunit alpha/IL-3R-alpha/IL-3RA)

Immunogen:

A synthetic peptide corresponding to a sequence in the middle region of human IL3RA(135-151aa QYDLYLNVANRRQQYEC).

Solubilization:

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Properties:

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Tips:

The IL3RA Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Storage condtions:

Keep the IL3RA Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Related articles:

1. Itoh, N., Yonehara, S., Schreurs, J., Gorman, D. M., Maruyama, K., Ishii, A., Yahara, I., Arai, K., Miyajima, A. Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science 247: 324-327, 1990. 2. Kitamura, T., Sato, N., Arai, K., Miyajima, A. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta-subunit for the human IL-3 and GM-CSF receptors. Cell 66: 1165-1174, 1991.

Synonyms:

CD123 antibody|CD123 antigen antibody|hIL 3Ra antibody|hIL-3Ra antibody|hIL3Ra antibody|IL 3 receptor alpha SP2 isoform antibody|IL 3R alpha antibody|IL-3 receptor subunit alpha antibody|IL-3R subunit alpha antibody|IL-3R-alpha antibody|IL-3RA antibody|IL3 Receptor alpha antibody|IL3R antibody|IL3Ra antibody|IL3RA_HUMAN antibody|IL3RAX antibody|IL3RAY antibody|IL3RX antibody|IL3RY antibody|Interleukin 3 receptor alpha chain antibody|Interleukin 3 receptor, alpha(low affinity) antibody|Interleukin 3 receptor, alpha antibody|Interleukin-3 Receptor alpha antibody|Interleukin-3 receptor subunit alpha antibody|Interleukin3 receptor antibody|Interleukin3 receptor, Y-chromosomal antibody

Background:

IL3RA(INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123(Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.