Rabbit anti NHE6 / Sodium/hydrogen exchanger 6

Antibody's reacts with:

Human

Antibody is raised in:

Rabbit

Storage:

-80ºC

Protein number:

see ncbi

Clone:

Polyclonal

Application:

Western blot

Antibody's specificity:

No Data Available

Category:

Primary Antibodies

Latin name:

Oryctolagus cuniculus

Antibody's reacts with these species:

This antibody doesn't cross react with other species

Antigen-antibody binding interaction:

Rabbit anti NHE6 / Sodium/hydrogen exchanger 6 Antibody

Antibody come from:

Synthetic peptide derived from human sphingomyelin phosphodiesterase 3

Other description:

Provided as solution in phosphate buffered saline with 0.08% sodium azide. Ammonium Sulfate Precipitation

Long description:

Electroneutral exchange of protons for Na(+) and K(+) across the mitochondrial inner membrane. Contributes to organellar volume and calcium homeostasis.

Description:

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Antibody's suited for:

Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions. Protein appears to run lower than expected protein molecular weight. However, antibody is specific for the protein and band blocks when blocking peptide used.

Warnings:

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.

About:

Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Relevant references:

1. Hofmann, K., et al. Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase.; Proc. Natl. Acad. Sci. U.S.A. 97:5895-5900(2000)._x000B__x000B_2. Miura, Y., et al. Hydrolysis of sphingosylphosphocholine by neutral sphingomyelinases.; FEBS Lett. 557:288-292(2004)._x000B__x000B_3. Marchesini, N., et al. Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells.; J. Biol. Chem. 279:25101-25111(2004).