anti-Sodium Calcium Exchanger 1 Antibody [6H2]

Works with:

Rat

Monoclonal:

6H2

Ab raised in:

Mouse

Immunoglobulin:

IgG2B

NCBI GENE nr:

29715

Protein nr:

Q01728

GENE symbol:

Slc8a1

Ncbi nr:

Q01728

Omim nr:

1346652

KDa:

120/160

French translation:

anticorps

Type:

Monoclonal

Vial with antibody:

Lyophilized

Immuno application:

Western Blot

Antibodie's label:

unlabelled serum

Source:

Rattus norvegicus

Purity:

Protein G purified

Antigen:

Potassium Channel, Kv2.

Gene names:

Ncx, Ncx1, Solute carrier family 8 member 1,

Antigene name:

solute carrier family 8 (sodium/calcium exchanger), member 1

Properties:

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description:

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Keep at:

Sodium Calcium Exchanger 1 antibody can be stored at -20 grades C. After reconstitution in 50 μl PBS, the antibody should be aliquot and stored at -20 grades C and is stable at -20 grades C for at least 1 year. Ambient shipment is suitable for both international and domestic.

Antibody advice:

Sodium Calcium Exchanger 1 antibody can be used for strong and specific immunolabeling of the Na/Ca exchanger NaCX-1 (Mr ~120k and 160k) with a broad tissue and species reactivity. Applications include Dot Blots (DB) and Western Blots (WB). When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Gene info:

Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX1, NaCX2, and NaCX3), and two in the NaCKX family (NaCKX1 and NaCKX2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling.